| The pharmaceutical company who manufactured this drug wanted a new money-maker to capitalize on the growing type 2 diabetes market. The FDA provided fast track approval for the drug in the summer of 1997. In December 1997, British regulatory officials withdrew Rezulin from the market after 6 Rezulin-related deaths were reported.3
However, in the U.S., pharmaceutical representatives promoted the drug to doctors, and doctors prescribed it, without qualms, to their patients. It was the newest, it was the best, and it had FDA approval. |
| In a world where there is a large percentage of overweight people, only 30% of this group ever develop type 2 diabetes. (After numerous investigative reports were broadcast on TV stations in the U.S. and Canada, the ADA finally reversed their long-held official position that, "All diabetics can safely and efficaciously be transferred from animal based insulins to the human insulins.")
Have you ever wondered who pays for all the conferences, trips by well-known people, marathons, and seminars in removed but well-known places (i.e. |
| B) The Continuous Glucose Monitoring System is Useful for Detecting Unrecognized Hypoglycemia in Patients with Type 1 and type 2 diabetes but Is Not Any Better Than Frequent Capillary Glucose Measurements for Improving Metabolic Control. Compare this to reference #5 above. Who is right?
C) Incidence and Predictive Criteria of Nocturnal Hypoglycemia in Young Children with Insulin-Dependent Diabetes Mellitus. Blood glucose levels at 11 p.m. were not good indicators of hyperinsulin anemia (too much insulin) at 2 a.m. The same bG at 11 p.m. |
Jonny Bowden, Ph.D., C.N.S.
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 Beltsville Human Nutrition Research Center in Maryland, tested the effects of cinnamon on blood glucose as well as other important blood measures like triglycerides and cholesterol in people with type 2 diabetes: They found that even 1 g of cinnamon a day reduced blood sugar (18 percent to 29 percent), triglycerides (23 percent to 30 percent), LDL cholesterol (7 percent to 27 percent), and total cholesterol (12 percent to 26 percent). Not bad for a little brown spice you can get in any grocery store for a couple of bucks.
More recently, in a series of ingenious experiments, Harry Preuss, M.D. |
Dr. Vern Cherewatenko and Paul Perry
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 Another study points to a possible link between dioxin and the startling jump in type 2 diabetes among children around the world. Researchers speculate a connection between obesity, diabetes, and the body's storage of chemicals such as dioxin in fat cells.
People who take protease inhibitors, a powerful new drug to Ueat people with AIDS, appear to have an increased risk of diabetes. The actual risk of diabetes from protease inhibitors is not known because many of the estimated 150,000 HIV-positive Americans on the drug may have undetected hyperglycemia. |
| Maxine illustrates a severe case of type 2 diabetes. Maxine had been placed on insulin for her diabetes about two years prior to seeing me. She had moved to the area recendy and was establishing new relationships and finding a new doctor, dentist, and drugstore.
The move was emotionally trying and had left her feeling depressed and fatigued. She felt that her Prozac was not helping her as it used to, and she was frustrated with herself for the short temper she was exhibiting toward her family. Store-bought cookies seemed to help with some of her anxiety, but only temporarily. |
| It is one that can lead you out of the dangerous terrain defined by the disease known as type 2 diabetes. Whether you have diabetes or you are at risk for getting it, now is the time to use the information in this book to put your health in order.
Web Sites
These Web site references are listed in the following format:
• Host—author of site.
• URL address.
• Topic areas.
Alternative Medicine Home Page http: //www.pitt.edu/~cbw/ altm.html Resource for finding information relating to alternative medicine.
American Association of Diabetes Educators http://www.diabetesnet.com/aade. |
Ray D. Strand
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 Magnesium deficit has been associated with both type 1 and type 2 diabetes, as well as an increased risk of retinopathy in diabetic patients. Studies show that when this deficiency is corrected in the elderly, insulin function improves significantly."1
Unfortunately, diagnosing magnesium deficiency is very difficult. Typically, serum magnesium levels are tested where only a trace amount of the body's total magnesium is located. Cellular levels of magnesium are much more sensitive and accurate; however, these can be tested only in research labs, not in hospitals. |
Dr. Vern Cherewatenko and Paul Perry
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| Well, there is, and it is this: type 2 diabetes is a disease of lifestyle that can be reversed by adopting healthy habits. You don't have to be a victim of this terrible disease if you take control and decide you are going to beat it.
Yes, diabetes is beatable, and with this book you have the tools to do just that. As I tell my patients, "I can give you the road map to get to wellness, but you have to drive the car."
Drive carefully. |
Ray D. Strand
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| I strongly believe that in type 2 diabetes mellitus, physicians should rely on medication as a last resort.
Doctors Are Treating the Wrong Thing
In a review article for the Mayo Clinic, Or. James O'Keefe stated: "Therapeutic efforts in patients with diabetes have focused predominantly on normalizing increased blood sugar levels while often ignoring many of these other modifiable risks, which are caused by the underlying insulin resistance."7
This accounts, in part, for the fact that 80 percent of diabetics still die of cardiovascular disease. |
Dr. Vern Cherewatenko and Paul Perry
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| Tagamet, a medication available since the early 1980s for ulcers and heartburn, is showing promise for people with type 2 diabetes. Researchers at the University of Oslo in Norway found that Tagamet given in a liquid form helped test subjects shed weight, lower blood pressure, and control blood glucose levels.
Tests
• Diabetic kidney disease is the leading cause of people undergoing kidney dialysis. A new test has been developed that detects kidney disease early, allowing for earlier detection and treatment. |
Dr. Sharon Moalem
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 That means it's currently much more common in the developed world because easy access to high-calorie, low-nutrient junk food means so many more people are obese—but it seems clear that the predisposition to type 2 diabetes exists across population groups. There are higher levels of incidence in certain populations, of course—but even that tends to occur hand in hand with higher levels of obesity. The Pima Indians of the southwestern United States, for example, have a staggering rate of diabetes—nearly half of all adults. |
| Increasingly, adult-onset diabetes is becoming a misnomer: skyrocketing rates of childhood obesity are leading to increasing numbers of children who have type 2 diabetes.)
Some researchers believe that Type 1 diabetes is an autoimmune disease—the body's natural defense system incorrectly identifies certain cells as outside invaders and sets out to destroy them. In the case of Type 1 diabetes, the cells that fall victim to this biological friendly fire are the precise cells in the pancreas responsible for insulin production. |
Andreas Moritz
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 One of these studies, the Nurses' Health Study, also found that regularly eating nuts reduces the chance of developing type 2 diabetes by 21-27%. Besides monounsaturated fats, nuts are rich in vitamins, minerals, and other substances that are beneficial to your health. For example, walnuts contain a type of omega-3 fat similar to fish oil, and almonds contain calcium and vitamin E. Nuts are also good sources of digestible protein and beneficial fiber. |
Dr. Vern Cherewatenko and Paul Perry
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| The contraceptives identified as producing the greatest risk of type 2 diabetes were progestin-only pills, progestin implants (Norplant), and estrogen-progestin combinations with the strongest progestins.
A different study from Harvard Medical School placed the blame squarely on obesity. Women who have diabetes or who are at risk for developing it—either through a previous gestational diabetic episode or a history of diabetes in their families—should talk with their doctors about taking combination contraceptives with the lowest dose and potency of progestin. |
Dr. Steve Blake
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 Chromium deficiency may be a contributing factor in both type 2 diabetes and impaired glucose tolerance. Heavy exercise may increase the amount of chromium needed.
Summary for Chromium
Main function: assists insulin in controlling blood sugar. Adequate Intakes: adults, 20 meg to 35 meg. Toxicity: no reports of toxicity from trivalent chromium. CM] Hexavalent chromium is highly toxic.
Tolerable upper intake level has not been set. Deficiency may interfere with the control of blood sugar. Sources: whole grain products, broccoli, green beans, grape juice, and spices. |
Gerald E. Markle and Frances B. McCrea
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 Suffice it to say: obesity, particularly morbid obesity, is associated with cardiovascular disease, cancer, and type 2 diabetes. A longitudinal study of more than a half million adults aged fifty to seventy, sponsored jointly by the NIH and AARP, found that overweight and obesity were associated with higher death rates for all demographic categories. Increased risk was highest for those who never smoked: death rates were
20-40 percent higher for the overweight, and two to three times higher for the obese. |
Dr. Steve Blake
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| The clinical signs of type 2 diabetes include elevated blood sugar levels and insulin resistance.
Cell membranes have insulin receptors. The sensitivity of this receptor to insulin can be improved by chromium. Insulin binds to the insulin receptor in the cell membrane to activate the receptor, as seen in Figure 13-4. The activation of the insulin receptor enables glucose and chromium to enter the cell. Chromium binds to the insulin receptor and enhances its activity. With available chromium, more glucose enters the cell. |
Marshall Editions
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 Formula two: This can be used to treat either Type 1 or type 2 diabetes. Symptoms include overheating and emotional disturbance, fever, perspiration, anxiety, irritability, anger, constipation, strong thirst, and a yellow, dry tongue. Place 12 g of Zhi Zi (Cape Jasmine fruit), 12 g of Yu Zhu (atractylodes rhizome), 10 g of Huang Qin (baical skullcap root), 12 g of Tian Hua Fen (trichosanthes root), 10 g of Chai Hu (hare's ear root), 12 g of Zhi Mu (anemarrhena rhizome), and 12 g Dan Pi (cortex of tree peony root) in a ceramic pot and add 3—4 cups of water. |
Too Profitable to CureBrent Hoadley, Ph.D.
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| New Strategies for Basal Insulin Treatment in type 2 diabetes Mellitus. G. Dailey, Clinical Therapy 2004, 6/26 (6): 889-901.
• Structural and Morphological Characteristics of Ultra-lente Insulin Crystals by Atomic Force Microscopy: Evidence of Hydrophobically Driven Assembly. DeFellipis et al, Biophysics Journal 1998 Sept. 75(3): 1172-9.
• Deaths Associated with "Human" Insulin Omitted from Review. News Release. Insulin Dependent Diabetes Trust, 7/24/2000.
• Drugmakers Spend More on Dividends than Research. Julie Appleby, USA Today, 15 October 2004. |
Andreas Moritz
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| At the beginning stages of type 2 diabetes, the pancreas tries to respond to the increasing congestion of the blood vessel walls (with excessive proteins) and, possibly, to an excessive sugar or starch consumption, by secreting extra large amounts of insulin. By constantly producing disproportionate amounts of insulin, the cells become even further resistant to insulin. By blocking out insulin (along with vital nutrients) the cells attempt to protect themselves against the cell-damaging effects of too much insulin, or else they would have to face cell mutation. |
| Would you have believed even 25 years ago that hardening of the arteries, high blood pressure, type 2 diabetes and obesity would one day be as common among children as they are today? Childhood obesity increased from 5 percent in 1964 to about 20 percent today—and it is rising. Children spend an average of 5 to 6 hours a day on sedentary activities, including watching television, using the computer, and playing video games. Today's children are bombarded and brainwashed with well-crafted TV ads from fast-food chains and other purveyors of high-fat, high-sugar meals and snacks. |
| And in the case of type 2 diabetes, the body's 60 trillion cells don't just reject insulin because they have developed a dislike to it. In both situations, the cells are prevented from doing their job for a number of reasons, all of which are basically under our control. If we stop destroying the cells directly or indirectly by the way we eat and live, they can just as easily be reprogrammed, nursed back to life or be replaced by new ones.
Healing the pancreas is not so much different than healing a broken bone. |
Dr. Sharon Moalem
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| On top of daily insulin doses, Type 1 requires vigilant attention to blood sugar levels and a su-perdisciplined approach to diet and exercise.
In type 2 diabetes, the pancreas still produces insulin—sometimes even at high levels—but the level of insulin production can eventually be too low or other tissues in the body are resistant to it, impairing the absorption and conversion of blood sugar. |
| A baby girl born in 2000 now has a 40percent chance—almost a coin toss—of developing of type 2 diabetes, and that's directly related to the huge surge in heavy kids.
What's even sadder is that many of these children are showing symptoms of obesity-related illness while they're still kids. One recent study showed that about 60 percent of obese five- to ten-year-olds already exhibited at least one major risk factor for heart disease—high cholesterol, high blood pressure, high triglycerides, or high sugar levels. Of those kids, 25 percent had more than one risk factor. |
Jack Challem
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 In one study, researchers gave cinnamon to 60 overweight people with type 2 diabetes. The dosages were 1, 3, or 6 grams daily for 40 days. People taking cinnamon had decreases in blood sugar ranging from 18 to 29 percent. Although you can buy cinnamon in capsules, it is far less expensive to purchase the ground spice and sprinkle it on oatmeal or fruit, such as apples, cantaloupe, or berries. Take 1 to 6 grams daily. One gram of cinnamon is about one-quarter teaspoon of the spice, so 4 grams would equal 1 tea-spoonful.
Ginseng. |
Mehmet C. Oz., M.D. and Michael F. Roizen, M.D.
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 Eventually, especially in people with family histories of type 2 diabetes (evidence of a genetic predisposition to the disease), our pancreatic
FACTOIP
The diabetes drug metformin (Glucophage and others) helps control and prevent diabetes by helping your muscles use more glucose and getting your liver to stop producing too much glucose (side effects include intestinal problems). The ideal treatment is to get your eating and activity in line and use the drug as a complement until the lifestyle changes kick in. |
Michael Pollan
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 But while it is true that our life expectancy has improved dramatically since 1900 (rising in the United States from forty-nine to seventy-seven years), most of that gain is attributed to the fact that more of us are surviving infancy and childhood; the life expectancy of a sixty-five-year-old in 1900 was only about six years less than that of a sixty-five-year-old living today* When you adjust for age, rates of chronic diseases like cancer and type 2 diabetes are considerably higher today than they were in 1900. |
| They observed too that when one Western disease arrived on the scene, so did most of the others, and often in the same order: obesity followed by type 2 diabetes followed by hypertension and stroke followed by heart disease.
In the years before World War II the medical world entertained a lively conversation on the subject of the Western diseases and what their rise might say about our increasingly industrialized way of life. |
| Based on fourteen years of follow-up, Willett and his colleagues calculated that, had the entire cohort adopted these behaviors, 80 percent of coronary heart disease; 90 percent of type 2 diabetes, and more than 70 percent of colon cancer cases could have been avoided. This analysis suggests that the worst effects of the Western diet can be avoided or reversed without leaving civilization. Or, as Willett writes, "the potential for disease prevention by modest dietary and lifestyle changes that are readily compatible with life in the 21st century is enormous." From Walter C. |
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